Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Varicose Veins II: Diagnostic Studies and Interprofessional Care01:26

Varicose Veins II: Diagnostic Studies and Interprofessional Care

Varicose veins, or varicosities, develop when the valves in the veins, which control blood flow, weaken or damage. It causes blood to pool and the veins to enlarge. Understanding the clinical manifestations, diagnostic approaches, and management options for varicose veins is crucial for effective treatment and relief.Clinical manifestationsClinical manifestations of varicose veins include a heavy, achy feeling or pain after prolonged standing or sitting. This discomfort can often be relieved by...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Think This Can't Happen to You?

Clinical journal of oncology nursing·2025
Same author

Introduction.

Seminars in oncology nursing·2018
Same author

A Pathway to Publishing an Oncology Nursing Book.

Seminars in oncology nursing·2018
Same author

Publishing in Oncology Nursing: A Look to the Past, Present, and Future.

Seminars in oncology nursing·2018
Same author

2016 Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology

Oncology nursing forum·2017
Same author

2016 Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology.

Journal of oncology practice·2016

Related Experiment Video

Updated: Jul 13, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

Extravasation management.

Lisa Schulmeister1

  • 1FAAN, 282 Orchard Road, River Ridge, LA 70123-2648, USA. LisaSchulmeister@hotmail.com

Seminars in Oncology Nursing
|August 19, 2007
PubMed
Summary

Managing vesicant extravasations requires awareness of limited evidence. Recommended treatments include specific antidotes and supportive care to prevent tissue damage from chemotherapy agents.

Area of Science:

  • Oncology
  • Pharmacology
  • Dermatology

Background:

  • Vesicant chemotherapy agents can cause severe tissue damage upon extravasation.
  • Understanding injury mechanisms is crucial for effective management.

Purpose of the Study:

  • To describe injury mechanisms of DNA-binding and non-binding vesicants.
  • To review current clinical management procedures for vesicant extravasations.

Main Methods:

  • Literature review of journal articles.
  • Analysis of published case reports.
  • Incorporation of personal clinical experience.

Main Results:

  • Limited evidence and consensus exist for vesicant extravasation management.

Related Experiment Videos

Last Updated: Jul 13, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
07:22

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

Published on: March 14, 2025

  • Manufacturer-recommended antidotes: sodium thiosulfate for mechlorethamine and hyaluronidase for plant alkaloids.
  • Intravenous dexrazoxane shows efficacy in preventing necrosis from anthracycline extravasation; dimethyl sulfoxide requires further study.
  • Conclusions:

    • Nurses must stay informed about evidence for extravasation treatment.
    • Nurses are vital in preventing, detecting, managing, and documenting these injuries.
    • Informed nurses act as patient advocates to minimize harm from vesicant extravasation.