Related Experiment Video
Updated: Jul 13, 2026

Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
Hypersensitivity reactions to biological drugs
1Northwestern Memorial Hospital, 251 E. Huron-Feinberg Pavilion 4-508, Chicago, IL 60611, USA. bgobel@nmh.org
Objectives:
To review the current evidence regarding hypersensitivity reactions related to the administration of biological drugs in the management of cancer, and to provide the nurse with appropriate interventions related to the management of hypersensitivity reactions.
Data Sources:
Review articles and research studies from the medical and nursing literature.
Conclusion:
Current evidence is available regarding the types of reactions that are associated with the administration of biological drugs in the management of cancer. Medical and nursing studies that review the most effective management of hypersensitivity reactions related to the administration of biological drugs. A review of "best practice" is offered in this article regarding the management of hypersensitivity reactions related to the administration of biological drugs.
Implications For Nursing Practice:
Nurses play a key role in the early identification of hypersensitivity reactions. Management of hypersensitivity reactions must be rapid for optimal patient outcomes.
Related Concept Videos
Allergic Drug Reactions
Drug Toxicity: Allergic Reactions
Hypersensitivity Reactions: Cytolytic Reactions
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Hypersensitivity Reactions: Immune-Complex Reactions
Allergic Reactions: Anaphylaxis

