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Updated: Jul 13, 2026
10:22
Basophil Activation Test for Investigation of IgE-Mediated Mechanisms in Drug Hypersensitivity
Published on: September 16, 2011
Hypersensitivity reactions to biological drugs
1Northwestern Memorial Hospital, 251 E. Huron-Feinberg Pavilion 4-508, Chicago, IL 60611, USA. bgobel@nmh.org
Seminars in Oncology Nursing
|August 19, 2007
Summary
This review summarizes evidence on hypersensitivity reactions to biological drugs in cancer care. It offers nurses practical interventions for managing these reactions effectively.
Area of Science:
- Oncology
- Pharmacology
- Immunology
Background:
- Biological drugs are increasingly used in cancer management.
- Hypersensitivity reactions (HSRs) are a significant concern with biological therapies.
- Prompt identification and management of HSRs are crucial for patient safety.
Purpose of the Study:
- To review current evidence on hypersensitivity reactions associated with biological drugs in cancer treatment.
- To provide nurses with evidence-based interventions for managing these reactions.
- To outline best practices for the nursing management of HSRs in oncology.
Main Methods:
- A comprehensive review of medical and nursing literature.
- Inclusion of review articles and original research studies.
- Synthesis of evidence on HSR types and management strategies.
Main Results:
- Evidence confirms various hypersensitivity reactions linked to biological cancer drugs.
- Effective management strategies for HSRs are identified in medical and nursing literature.
- Best practice guidelines for managing HSRs are presented.
Conclusions:
- Nurses are vital in the early detection of hypersensitivity reactions.
- Rapid intervention is essential for optimal patient outcomes during HSRs.
- This review provides a framework for best practice in managing HSRs to biological drugs in cancer care.
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