Related Experiment Video
Updated: Jul 13, 2026

Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
Published on: January 17, 2025
Transducing particles of Staphylococcus aureus pathogenicity island SaPI1 are comprised of helper phage-encoded
Sandra M Tallent1, Timothy B Langston, Richard G Moran
1Department of Microbiology and Immunology, VCU, Richmond, VA 23298-0678, USA.
Abstract:
The relationship between the composition of SaPI1 transducing particles and those of helper phage 80alpha was investigated by direct comparison of virion proteins. Twelve virion proteins were identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and mass spectrometry; all were present in both 80alpha and SaPI1 virions, and all were encoded by 80alpha. No SaPI1-encoded proteins were detected. This confirms the prediction that SaPI1 is encapsidated in a virion assembled from helper phage-encoded proteins.
Related Concept Videos
DNA Bacteriophages
Transduction
Determinants of Bacterial Pathogenicity and Virulence
Lysogenic Cycle of Bacteriophages
Gram-negative Bacterial Protein Secretion Systems
Lytic Cycle of Bacteriophages

