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An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation
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Hat1: the emerging cellular roles of a type B histone acetyltransferase

M R Parthun1

  • 1Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, USA. parthun.1@osu.edu

Oncogene
|August 19, 2007
PubMed

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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Histone Modification02:32

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