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Rapid development of multiple squamous-cell carcinomas during chronic granulocytic leukemia
P Disdier1, J R Harle, J J Grob
1Service de Médecine Interne du Prof. P.J. Weiller, Clinique Médicale B, Hôpital de La Timone, France.
Dermatologica
|January 1, 1991
Abstract:
We report a 65-year-old patient who presented a rapid eruption of keratoses on sun-exposed areas and an explosive transformation into several squamous-cell carcinomas, occurring during the accelerated phase of a chronic granulocytic leukemia. Clinical findings resembled those usually described in xeroderma pigmentosum. The role of immunosuppression, chemotherapy and possible genetic predisposition is discussed.