Related Experiment Video
Updated: Jul 13, 2026

BrainBeats as an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals
Published on: April 26, 2024
Characterization of interdependency between intracranial pressure and heart variability signals: a causal spectral
Xiao Hu1, Valeriy Nenov, Paul Vespa
1Brain Monitoring and Modelling Laboratory, Division of Neurosurgery, University of California, Los Angeles, CA 90034, USA. xiaohu@ucla.edu
Abstract:
Causal coherence and generalized synchronization (GS) index were extracted from beat-to-beat mean intracranial pressure (ICP) and intervals between consecutive normal sinus heart beats (RR interval) that were recorded from 12 patients undergoing normal pressure hydrocephalus diagnosis. Data were organized into two groups including an ICP B-Wave group and a baseline control group. Maximal classic coherence (CC) between ICP and RR interval within [0.04, 0.15] Hz was found to be significantly greater than zero for both B-Wave and control groups with B-Wave CC greater than that of the baseline group. Causal coherence analysis further revealed that feedforward coherence due to RR interval's effect on ICP always exists for both B-Wave and baseline ICP state and no significant difference exists between two groups. On the other hand, feedback coherence from ICP to RR interval was enhanced during the occurrence of B-Wave. This finding regarding the enhanced directional, from ICP to RR interval, coupling between ICP and RR interval was also confirmed by a modified GS measure.
Related Concept Videos
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Neural Regulation of Blood Pressure
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
Measurement of Blood Pressure
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...

