[Larsen syndrome: clinical course and treatment of 22 cases]

In 1950 Joseph Larsen described patients with facial dysmophism, joint hyperelasticity and multiple dislocations. Frequency is 1/ 100,000 live births. Sporadic cases have been reported in the literature in recent years. We analyzed a total of 22 patients with Larsen syndrome, all of them treated in our institution. We report their alterations and management, whether surgical or orthopedic, with a minimum follow-up of three years. After the follow-up we concluded that conservative treatment is fundamental and surgical interventions are indicated for: adduct club foot, patellofemoral dislocation, and unilateral hip dislocation.