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Published on: August 8, 2025
Life-saving therapy for haemorrhaging liver adenomas using selective arterial embolization
J H M B Stoot1, E van der Linden, O T Terpstra
1Department of Surgery, Leiden University Medical Centre, Leiden, The Netherlands.
The British Journal of Surgery
|August 19, 2007
Summary
Selective arterial embolization is a safe and effective first treatment for bleeding hepatocellular adenomas, avoiding surgery and reducing tumor size. This interventional radiology technique offers a minimally invasive solution for managing these liver tumors.
Area of Science:
- Interventional Radiology
- Hepatobiliary Surgery
- Medical Oncology
Background:
- Management of ruptured hepatocellular adenoma (HA) remains controversial.
- Selective arterial embolization (SAE) is evaluated as a primary treatment modality.
Purpose of the Study:
- To assess the efficacy and safety of SAE for ruptured hepatocellular adenomas.
- To evaluate SAE's impact on tumor size and complications.
Main Methods:
- Retrospective analysis of 11 consecutive patients with ruptured HA treated between 2001 and 2006.
- All patients underwent SAE after initial hemodynamic support.
- Outcomes included bleeding control, complications, and tumor size changes.
Main Results:
- Successful hemorrhage control was achieved in 10 out of 11 patients with a single embolization; one patient required three embolizations.
- No patients necessitated emergency surgery.
- Follow-up (19 months median) showed no general or hepatobiliary complications.
- Significant reduction in adenoma size was observed (median diameter decreased from 7.0 to 2.5 cm, P < 0.001).
Conclusions:
- SAE is a safe and effective first-line treatment for hemorrhaging hepatocellular adenomas.
- Arterial embolization leads to a significant reduction in liver adenoma size.
