Related Experiment Video
Updated: Jul 13, 2026

Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
Published on: September 13, 2014
Hepatorenal syndrome
Sharon Turban1, Paul J Thuluvath, Mohamed G Atta
1Division of Nephrology, Johns Hopkins University, 1830 East Monument Street, Suite 416, Baltimore, Maryland 21205, USA.
Abstract:
Hepatorenal syndrome (HRS) is a "functional" and reversible form of renal failure that occurs in patients with advanced chronic liver disease. The distinctive hallmark feature of HRS is the intense renal vasoconstriction caused by interactions between systemic and portal hemodynamics. This results in activation of vasoconstrictors and suppression of vasodilators in the renal circulation. Epidemiology, pathophysiology, as well as current and emerging therapies of HRS are discussed in this review.
Related Concept Videos
Nephrotic Syndrome I : Introduction
Acute Kidney Injury II: Pathophysiology
Portal Hypertension
Nephrotic Syndrome II : Assessment and Medical Management
Kidney Transplant II: Surgical Procedure
Nephrotic Syndrome III : Nursing Management