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Related Experiment Videos

Horner syndrome.

Yu X Kong1, Gavin Wright, Konrad Pesudovs

  • 1Cardiothoracic Care Centre, Fitzroy, Victoria, Australia.

Clinical & Experimental Optometry
|August 19, 2007
PubMed
Summary
This summary is machine-generated.

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Horner syndrome, a disruption of the sympathetic nerve pathway, can indicate underlying cancers. Early diagnosis and treatment of these tumors led to complete resolution of the syndrome in our patient.

Area of Science:

  • Neurology
  • Oncology
  • Ophthalmology

Background:

  • Horner syndrome results from sympathetic pathway interruption to the eye and face.
  • Diagnosis is primarily clinical, supported by pharmacological testing and imaging.
  • Acquired Horner syndrome necessitates thorough investigation for underlying pathology.

Observation:

  • A patient presented with Horner syndrome, which revealed an underlying superior sulcus squamous cell carcinoma.
  • Coincidentally, a lower lobe adenocarcinoma was also identified in the same patient.
  • The patient's cancers were treated radically.

Findings:

  • Radical treatment of both squamous cell carcinoma and adenocarcinoma led to complete resolution of Horner syndrome.
  • The patient achieved disease-free survival for 18 months post-treatment.

Related Experiment Videos

  • This case highlights the importance of investigating Horner syndrome as a potential cancer indicator.

    • Implications:

    • Horner syndrome can be a critical early sign of potentially curable cancers.
    • Prompt diagnosis and multimodal treatment of associated malignancies are crucial for patient outcomes.
    • Understanding the anatomy and pathophysiology of Horner syndrome aids in diagnosing and managing its underlying causes.