Patients with Parkinson's disease can successfully remember to execute delayed intentions
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Updated: Jul 13, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Mareike Altgassen1, Jacqueline Zöllig, Ute Kopp
1Department of Psychology, University of Zurich, Zurich, Switzerland.
Abstract:
The present study investigated prospective memory in patients with Parkinson's disease (PD) and healthy controls. In addition, the influence of task importance on participants' performance was examined. Experimental settings required participants to focus either on the prospective or the ongoing task. The three main findings are (1) PD patients performed as well on a prospective memory task as healthy controls when the focus was laid on the prospective memory task, (2) their prospective memory performance was impaired when the ongoing activity was stressed, and (3) differences in working memory capacity were related to these differential effects. Results indicate that PD patients can perform event-based prospective memory tasks to a normal degree if the prospective task component is prioritized. Data also suggest that a reduced working memory capacity plays an important role in this process. Findings are discussed in terms of conceptual, methodological, and clinical implications.
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