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Updated: Jul 13, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Cardiologists' use of percutaneous coronary interventions for stable coronary artery disease
Grace A Lin1, R Adams Dudley, Rita F Redberg
1Division of General Internal Medicine, University of California-San Francisco School of Medicine, CA 94143-0124, USA.
Insights
Cardiologists often perform percutaneous coronary intervention (PCI) for stable coronary artery disease despite evidence of minimal benefit. Nonclinical factors like patient anxiety and medicolegal concerns influence decisions, highlighting a gap between knowledge and practice.
Area of Science:
- Cardiology
- Medical Decision Making
- Health Services Research
Background:
- Percutaneous coronary intervention (PCI) is frequently used for stable coronary artery disease.
- Current evidence indicates minimal benefit from PCI in these patients.
- The study investigates factors influencing cardiologists' decisions for elective PCI.
Purpose of the Study:
- To determine the influences on cardiologists' decisions to perform elective PCI.
- To understand the reasoning behind PCI use in stable coronary artery disease despite conflicting evidence.
Main Methods:
- Qualitative study utilizing 3 focus groups with cardiologists.
- Grounded theory analysis of discussions on hypothetical case scenarios.
- Involved interventional and noninterventional cardiologists in California.
Main Results:
- Cardiologists believed PCI benefits stable coronary artery disease patients, despite data showing no reduction in death or heart attack risk.
- Reasons for PCI included treating ischemia, the open artery hypothesis (especially with drug-eluting stents), avoiding regret, patient anxiety, and medicolegal factors.
- An "oculostenotic reflex" leads to intervention for most stenoses found during angiography, even in asymptomatic patients.
Conclusions:
- Widespread PCI use in stable coronary artery disease may stem from a disconnect between clinical knowledge and belief in PCI benefits.
- Nonclinical factors significantly impact physician decision-making processes.
- Future research should develop strategies to better integrate clinical evidence into medical decision-making.
Background:
Percutaneous coronary intervention (PCI) is commonly performed in patients with stable coronary artery disease, despite current evidence suggesting that such patients derive minimal benefit from the procedure. We sought to determine the influences on cardiologists' decision to perform elective PCI in patients with stable coronary artery disease.
Methods:
We conducted a qualitative study using 3 focus groups of interventional and noninterventional cardiologists in California. Participants discussed issues surrounding the decision to perform PCI using hypothetical case scenarios. We analyzed the data according to the principles of grounded theory.
Results:
Despite acknowledging data showing that PCI offers no reduction in the risk of death or myocardial infarction in patients with stable coronary artery disease, cardiologists generally believed that PCI would benefit such patients. Reasons given for performing PCI included belief in the benefits of treating ischemia and the open artery hypothesis, especially with drug-eluting stents; potential regret for not intervening if a cardiac event could be averted; alleviation of patient anxiety; and medicolegal considerations. Participants believed that, in patients undergoing coronary angiography, an "oculostenotic reflex" prevailed and all significant amenable stenoses would receive intervention, even in asymptomatic patients.
Conclusions:
The widespread application of PCI in stable coronary artery disease for indications unsupported by evidence may reflect discordance between cardiologists' clinical knowledge and their beliefs about the benefits of PCI. Nonclinical factors appear to have substantial influence on physician decision making. Future studies should focus on the development of methods to help providers more fully incorporate clinical evidence into their medical decision making.
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