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Updated: Jul 13, 2026

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
Published on: December 1, 2023
Exercise alone reduces insulin resistance in obese children independently of changes in body composition
Lana M Bell1, Katie Watts, Aris Siafarikas
1Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, Crawley, Western Australia 6009, Australia.
Context:
The number of obese children with insulin resistance and type 2 diabetes is increasing, but the best management strategy is not clear.
Objective:
The objective of this study was to assess the effect of a structured 8-wk exercise training program on insulin resistance and changes in body composition in obese children.
Design:
The study was 8 wk of structured supervised exercise intervention with outcome measures before and after the exercise period.
Subjects:
Fourteen obese children (12.70 +/- 2.32 yr; eight male, six female) with high fasting insulin levels were enrolled into the study.
Intervention:
INTERVENTION consisted of 8 wk of supervised circuit-based exercise training, composed of three fully supervised 1-h sessions per week.
Outcome Measures:
Outcome measures were assessed pretraining program and posttraining program and included insulin sensitivity (euglycemic-hyperinsulinemic clamp studies), fasting insulin and glucose levels, body composition using dual energy x-ray absorptiometry scan, lipid profile, and liver function tests.
Results:
Insulin sensitivity improved significantly after 8 wk of training (M(lbm) 8.20 +/- 3.44 to 10.03 +/- 4.33 mg/kg.min, P < 0.05). Submaximal exercise heart rate responses were significantly lower following the training (P < 0.05), indicating an improvement in cardiorespiratory fitness. Dual energy x-ray absorptiometry scans revealed no differences in lean body mass or abdominal fat mass.
Conclusion:
An 8-wk exercise training program increases insulin sensitivity in obese children, and this improvement occurred in the presence of increased cardiorespiratory fitness but is independent of measurable changes in body composition.
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