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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
04:30

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis

Published on: May 14, 2013

Carotid stenting for atherothrombosis

Emile R Mohler1

  • 1University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. mohlere@uphs.upenn.edu

Heart (British Cardiac Society)
|August 19, 2007
PubMed

Insights

Cerebrovascular accident (CVA), a leading cause of death, can result from carotid artery atherothrombosis. This review examines percutaneous interventions for treating this condition.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Cardiology

Background:

  • Cerebrovascular accident (CVA) is a major cause of mortality in North America and Europe.
  • CVAs are broadly classified as thrombotic or hemorrhagic.
  • Thrombotic CVAs stem from large vessel occlusion, small vessel occlusion, or embolization.

Purpose of the Study:

  • To review the current understanding of carotid atherothrombosis.
  • To evaluate percutaneous approaches for treating carotid atherothrombosis.

Main Methods:

  • Literature review of current understanding and data on carotid atherothrombosis.
  • Analysis of percutaneous interventions for carotid artery disease.

Main Results:

  • Large vessel occlusion, specifically carotid atherothrombosis, accounts for about 25% of CVAs.
  • Treatment options for carotid atherothrombosis include risk factor management, carotid endarterectomy, and percutaneous stenting.

Conclusions:

  • Carotid atherothrombosis is a significant contributor to CVA.
  • Percutaneous interventions represent an evolving treatment option for selected patients with carotid atherothrombosis.

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