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Updated: Jul 13, 2026

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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Carotid stenting for atherothrombosis.
1University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. mohlere@uphs.upenn.edu
Heart (British Cardiac Society)
|August 19, 2007
Summary
Cerebrovascular accident (CVA), a leading cause of death, can result from carotid artery atherothrombosis. This review examines percutaneous interventions for treating this condition.
Area of Science:
- Neurology
- Vascular Surgery
- Cardiology
Background:
- Cerebrovascular accident (CVA) is a major cause of mortality in North America and Europe.
- CVAs are broadly classified as thrombotic or hemorrhagic.
- Thrombotic CVAs stem from large vessel occlusion, small vessel occlusion, or embolization.
Purpose of the Study:
- To review the current understanding of carotid atherothrombosis.
- To evaluate percutaneous approaches for treating carotid atherothrombosis.
Main Methods:
- Literature review of current understanding and data on carotid atherothrombosis.
- Analysis of percutaneous interventions for carotid artery disease.
Main Results:
- Large vessel occlusion, specifically carotid atherothrombosis, accounts for about 25% of CVAs.
- Treatment options for carotid atherothrombosis include risk factor management, carotid endarterectomy, and percutaneous stenting.
Conclusions:
- Carotid atherothrombosis is a significant contributor to CVA.
- Percutaneous interventions represent an evolving treatment option for selected patients with carotid atherothrombosis.
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