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Hypomagnesemia in patients with type 2 diabetes
Phuong-Chi T Pham1, Phuong-Mai T Pham, Son V Pham
1Olive View-UCLA Medical Center, 14445 Olive View Drive, Department of Medicine, 2B-182, Nephrology Division, Sylmar, CA 91342, USA. pctp@ucla.edu
Clinical Journal of the American Society of Nephrology : CJASN
|August 21, 2007
Summary
Hypomagnesemia, or low magnesium levels, is common in type 2 diabetes, affecting up to 47.7% of patients. This condition is linked to numerous diabetic complications, necessitating routine monitoring and treatment.
Area of Science:
- Endocrinology
- Metabolic Disorders
- Nephrology
Background:
- Hypomagnesemia is more prevalent in type 2 diabetes mellitus (T2DM) patients.
- Clinician awareness of this link and its implications remains suboptimal.
- Magnesium's role in T2DM complications warrants further investigation.
Purpose of the Study:
- To review magnesium metabolism in T2DM.
- To determine the incidence of hypomagnesemia in T2DM.
- To identify factors contributing to hypomagnesemia and its associated complications.
Main Methods:
- Literature review of studies on magnesium metabolism.
- Analysis of reported incidence rates of hypomagnesemia in T2DM.
- Synthesis of data on contributing factors and complications.
Main Results:
- Hypomagnesemia incidence in T2DM ranges from 13.5% to 47.7%.
- Contributing factors include poor diet, autonomic dysfunction, and altered insulin metabolism.
- Hypomagnesemia is associated with poor glycemic control, cardiovascular disease, and microvascular complications.
Conclusions:
- The increased incidence of hypomagnesemia in T2DM is multifactorial.
- Routine magnesium monitoring and treatment are recommended for T2DM patients.
- Addressing hypomagnesemia may improve outcomes and reduce diabetic complications.
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