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Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

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Updated: Jul 13, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Peripheral arterial disease: a guide for nephrologists.

Stephanie S DeLoach1, Emile R Mohler

  • 1Department of Medicine, Renal, Electrolyte and Hypertension Division, University of Pennsylvania, Philadelphia, PA 19104, USA.

Clinical Journal of the American Society of Nephrology : CJASN
|August 21, 2007
PubMed
Summary

Peripheral arterial disease (PAD) is common in chronic kidney disease (CKD) patients and often overlooked. Early screening, diagnosis, and treatment of PAD are crucial for managing cardiovascular risk in CKD.

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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
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Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

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Last Updated: Jul 13, 2026

Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
14:52

Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication

Published on: December 11, 2013

Area of Science:

  • Nephrology
  • Cardiology
  • Vascular Medicine

Background:

  • Cardiovascular disease (CVD) is a leading cause of death in chronic kidney disease (CKD) patients.
  • Peripheral arterial disease (PAD) is a significant predictor of coronary artery disease and mortality in the general population.
  • CKD patients have an elevated risk of PAD, which is frequently underestimated.

Purpose of the Study:

  • To provide a comprehensive overview of peripheral arterial disease (PAD) in patients with chronic kidney disease (CKD).
  • To emphasize the epidemiology, screening, diagnosis, and treatment of PAD within the context of CKD.
  • To highlight the importance of recognizing PAD as a source of morbidity and a cardiovascular risk factor in CKD.

Main Methods:

  • Literature review focusing on epidemiological data, diagnostic strategies, and therapeutic interventions for PAD.
  • Emphasis on studies and guidelines relevant to the CKD population.
  • Synthesis of current knowledge on PAD management in nephrology.

Main Results:

  • PAD prevalence is significantly higher in CKD patients compared to the general population.
  • PAD is often asymptomatic or presents with non-specific symptoms in CKD patients, leading to delayed diagnosis.
  • Screening for PAD is recommended in high-risk CKD patients.
  • Aggressive management of cardiovascular risk factors is essential in CKD patients with PAD.

Conclusions:

  • PAD represents a substantial and often under-recognized contributor to cardiovascular morbidity and mortality in CKD.
  • Nephrologists play a critical role in the screening, diagnosis, and management of PAD in their patients.
  • Integrated care approaches are necessary to address the complex cardiovascular risks in CKD patients with PAD.