Related Experiment Video
Updated: Jul 13, 2026

Oral Combinational Antiretroviral Treatment in HIV-1 Infected Humanized Mice
Published on: October 6, 2022
HIV-1 and HIV-Associated Nephropathy 25 Years Later
Christina M Wyatt1, Paul E Klotman
1Mount Sinai School of Medicine, Box 1243, One Gustave L. Levy Place, New York, NY 10029. christina.wyatt@mssm.edu.
Abstract:
Twenty-five years after the first published description of AIDS, HIV-associated nephropathy (HIVAN) remains an important cause of kidney disease in HIV-infected patients. The pathogenesis of HIVAN involves direct HIV infection of the kidney, with both viral and host genetic factors playing an important role. The widespread use of antiretroviral therapy has influenced the epidemiology of HIV-related kidney disease, and the nephrology community should support efforts to improve access to therapy and limit HIV transmission in susceptible minority populations. This article reviews the history of HIV and HIVAN, focusing on advances in the understanding of pathogenesis, epidemiology, and treatment.
More Related Videos
Related Concept Videos
Diabetic Nephropathy
Retrovirus Life Cycles
Acute Kidney Injury III: Clinical Manifestations
Nephrotic Syndrome I : Introduction
Nephrotic Syndrome II : Assessment and Medical Management
Chronic Kidney Disease II: Clinical Manifestations

