Condensed nearest neighbor data domain description
Related Experiment Video
Updated: Jul 13, 2026

Using Solution NMR to Characterize Biomolecular Condensates Under Biphasic Conditions
Published on: April 17, 2026
1Dipartimento di Elettronica Informatica e Sistemistica, Università della Calabria, Italy. f.angiulli@deis.unical.it
Abstract:
A simple yet effective unsupervised classification rule to discriminate between normal and abnormal data is based on accepting test objects whose nearest neighbors distances in a reference data set, assumed to model normal behavior, lie within a certain threshold. This work investigates the effect of using a subset of the original data set as the reference set of the classifier. With this aim, the concept of a reference consistent subset is introduced and it is shown that finding the minimum cardinality reference consistent subset is intractable. Then, the CNNDD algorithm is described, which computes a reference consistent subset with only two reference set passes. Experimental results revealed the advantages of condensing the data set and confirmed the effectiveness of the proposed approach. A thorough comparison with related methods was accomplished, pointing out the strengths and weaknesses of one-class nearest-neighbor-based training set consistent condensation.
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