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Updated: Jul 13, 2026

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
Published on: August 14, 2013
Drug-induced acute myopia following chlorthalidone treatment
G Mahesh1, A Giridhar, S J Saikumar
1Giridhar Eye Institute, 28/2576 A, Ponneth Temple Road. Kadavanthra, Cochin - 682 020, Kerala, India. girieye@vsnl.com
Abstract:
We report a case of sudden loss of vision due to the development of acute myopia after the intake of chlorthalidone used for treating systemic hypertension. Clinically this was associated with ciliary spasm, shallow peripheral choroidal effusion and retinal striae at the macula with increase in macular thickness seen on optical coherence tomography. All these findings were reversed completely once the drug was discontinued. Development of acute myopia should be kept in mind as an adverse effect of a commonly used antihypertensive drug, namely chlorthalidone.
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