Related Experiment Video
Updated: Jul 13, 2026

In Vitro Differentiation of Human Mesenchymal Stem Cells into Functional Cardiomyocyte-like Cells
Published on: August 9, 2017
"Stemness" does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs)
1Tulane Center for Gene Therapy, Tulane University Health Sciences Center, New Orleans, Louisiana, USA. dprocko@tulane.edu
Abstract:
There has recently been an explosion of interest in adult stem/progenitor cells that have the potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous announcements of clinical trials in which the cells are used to treat individuals with a broad range of diseases. At the same time, the data present a paradox-the cells originally attracted attention because of their stem-cell-like properties, but the cells frequently repair injured tissues without much evidence of either engraftment or differentiation.
Related Concept Videos
Mesenchymal Stem Cells
Tissue Renewal without Stem Cells
However, failure of such a system...
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Source And Potency Of Stem Cells
Multipotency of Hematopoietic Stem Cells
Stem Cell Niche
