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Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Multiple bilateral choroidal metastasis from anal melanoma
James Haddow1, Danayya Muthapati, Ilyas Arshad
1Department of Surgery, Pilgrim Hospital, Sibsey Road, Boston, UK.
International Journal of Clinical Oncology
|August 19, 2007
Summary
Anal canal melanoma can metastasize to the choroid, causing visual disturbances. Orbital radiotherapy effectively treated these ocular metastases, leading to significant visual recovery.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Melanoma, a malignant neoplasm of melanocytes, can occur in various locations, including the anal canal.
- Metastatic disease from primary tumors is a significant cause of morbidity and mortality.
- Choroidal metastases represent secondary malignant deposits in the choroid layer of the eye.
Observation:
- A 58-year-old woman presented with bleeding per rectum due to anal canal melanoma.
- The patient subsequently developed visual disturbances.
- Ophthalmic examination revealed bilateral multiple choroidal metastases, indicative of widespread systemic disease.
Findings:
- The anal canal melanoma metastasized to the choroid, presenting as bilateral ocular lesions.
- Multiple systemic metastases were also identified.
- Orbital radiotherapy was administered to target the ocular metastases.
Implications:
- This case highlights the potential for anal canal melanoma to metastasize to the choroid.
- Orbital radiotherapy demonstrated efficacy in achieving near-complete resolution of ocular metastases.
- Early detection and multimodal treatment approaches are crucial for managing metastatic melanoma.

