Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

797
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
797
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.3K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.3K
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

1.5K
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.5K
Autoimmune Disorders01:29

Autoimmune Disorders

2.0K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.0K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

433
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
433
Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

957
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
957

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nuclear shell structure governs short-range nucleon pairing.

Nature·2026
Same author

Screening for undiagnosed pancreatic exocrine insufficiency (PEI) in a cohort of diabetic patients using faecal elastase testing and PEI scoring system.

Acta diabetologica·2024
Same author

A systematic review of the effects of temperature and precipitation on pollen concentrations and season timing, and implications for human health.

International journal of biometeorology·2021
Same author

A novel value-based scoring system for endoscopic ultrasound-guided drainage of pancreatic fluid collections: a single-centre comparative study of plastic and lumen-apposing metal stents (NOVA study).

European journal of gastroenterology & hepatology·2020
Same author

Emergent repair of a fourth-degree perineal tear - a video vignette.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2020
Same author

Incidence of Asymptomatic Chiari Malformation

Irish medical journal·2019
Same journal

Trimester-Specific Safety of Laparoscopic versus Open Abdominal Surgery During Pregnancy: A Systematic Review and Meta-analysis.

The British journal of surgery·2026
Same journal

The Gut Microbiome in Surgical Oncology: Mechanisms, Perioperative Outcomes, and Therapeutic Opportunities.

The British journal of surgery·2026
Same journal

Patient-led, home-based follow-up for colorectal cancer: the DISTANCE multicentre stepped-wedge cluster-randomised trial.

The British journal of surgery·2026
Same journal

Correction to: Reduced secretory efficiency in parathyroid carcinoma: diagnostic value of the PTH-to-tumour-volume ratio.

The British journal of surgery·2026
Same journal

Global disparities in hepatocellular carcinoma outcomes: multicentre study.

The British journal of surgery·2026
Same journal

Surgical Outcomes from Nationwide Implementation of the International Best-Practice for Locally Advanced Pancreatic Cancer (PREOPANC-4) study.

The British journal of surgery·2026
See all related articles

Related Experiment Video

Updated: Feb 27, 2026

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

Published on: January 9, 2026

616

Autoimmune pancreatitis.

D P Toomey1, N Swan, W Torreggiani

  • 1Professorial Surgical Unit, University of Dublin, Trinity College, Adelaide and Meath Hospitals-National Children's Hospital, Tallaght, Dublin 24, Ireland.

The British Journal of Surgery
|August 19, 2007
PubMed
Summary
This summary is machine-generated.

Autoimmune pancreatitis, a form of chronic pancreatitis, is often mistaken for pancreatic cancer. Early diagnosis and steroid treatment can lead to dramatic improvements, highlighting the need for careful evaluation.

More Related Videos

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
06:44

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Published on: February 28, 2021

4.6K
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

15.1K

Related Experiment Videos

Last Updated: Feb 27, 2026

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice
14:39

A Simple and Rapid Method for Simultaneous Isolation of Primary Islets and Primary Pancreatic Acinar Cells from Mice

Published on: January 9, 2026

616
A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion
06:44

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Published on: February 28, 2021

4.6K
Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis
10:52

Preparation of Mouse Pituitary Immunogen for the Induction of Experimental Autoimmune Hypophysitis

Published on: December 17, 2010

15.1K

Area of Science:

  • Gastroenterology
  • Immunology
  • Oncology

Background:

  • Autoimmune pancreatitis (AIP) is a distinct form of chronic pancreatitis characterized by lymphoplasmacytic infiltrate.
  • Approximately 2% of pancreatic masses resected for suspected malignancy are AIP.
  • AIP is increasingly recognized as a distinct clinical entity.

Purpose of the Study:

  • To review the literature on autoimmune pancreatitis.
  • To summarize key diagnostic features and treatment outcomes.
  • To emphasize the importance of differentiating AIP from pancreatic cancer.

Main Methods:

  • Comprehensive literature search of Medline and PubMed databases.
  • Systematic review of identified articles and their reference lists.
  • Synthesis of information regarding clinical presentation, diagnosis, and management.

Main Results:

  • Patients typically present with obstructive jaundice, abdominal pain, and weight loss, often with imaging suggestive of malignancy.
  • Preoperative diagnosis is facilitated by elevated serum IgG4 levels, specific autoantibodies, characteristic imaging, and a biopsy negative for malignancy.
  • Steroid therapy is effective, leading to significant clinical improvement.

Conclusions:

  • Autoimmune pancreatitis is an important differential diagnosis for pancreatic masses.
  • Prompt diagnosis and steroid treatment can yield excellent outcomes.
  • Misdiagnosis of pancreatic cancer can be avoided with careful clinical and diagnostic evaluation.