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Updated: Jul 13, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
Carpal tunnel syndrome: using self-report measures of disease to predict treatment response
Jefferson J Kaye1, John M Reynolds
1Ochsner Clinic Foundation, New Orleans, LA 70121, USA. jkaye@ochsner.org
Abstract:
Initial self-report assessments of symptom severity in patients with carpal tunnel syndrome was retrospectively examined. At initial evaluation, 86 patients completed a self-administered questionnaire previously shown to be reproducible, internally consistent, and responsive to clinical change. Within the next 2 years, 50 patients underwent carpal tunnel release; of the other 36 patients, 23 were managed adequately with conservative treatment alone, and 13 were lost to follow-up. Initial mean symptom severity scores were statistically significantly higher for the surgery group (P = .000012). Significantly higher symptom severity scores on self-administered questionnaires at initial evaluation from patients who eventually undergo carpal tunnel release may be of value in planning treatment.
