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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:

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Related Experiment Video

Updated: Jul 13, 2026

Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing
10:29

Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing

Published on: July 6, 2016

[Q fever].

Zuzana Kalinová1, Erik Dorko, Lýdia Cisláková

  • 1Clinic of Infectious Diseases, Medical Faculty Kosice, Slovak Republic. kalinovz@pobox.sk

Klinicka Mikrobiologie a Infekcni Lekarstvi
|August 19, 2007
PubMed
Summary

Coxiella burnetii causes Q fever, a disease transmitted by inhaling contaminated aerosols from animals like cattle and goats. Treatment involves broad-spectrum antibiotics, with diagnosis based on antibody presence.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Bacteriology

Context:

  • Coxiella burnetii is a Gram-negative coccobacillus responsible for Q fever.
  • It infects host monocytes and macrophages, exhibiting a complex developmental cycle.
  • The bacterium displays phase variation from virulent phase I to avirulent phase II.

Purpose:

  • To provide a comprehensive overview of Coxiella burnetii, its characteristics, and Q fever.
  • To detail the bacterium's lifecycle, reservoirs, transmission, and clinical manifestations.
  • To outline diagnostic methods and therapeutic strategies for Q fever.

Summary:

  • Coxiella burnetii, the agent of Q fever, is a highly resistant Gram-negative bacterium found in livestock.
  • Transmission to humans occurs via inhalation of aerosols, leading to acute (flu-like illness, pneumonia, hepatitis) or chronic (endocarditis-like) disease.

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Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
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The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii
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The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii

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Related Experiment Videos

Last Updated: Jul 13, 2026

Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing
10:29

Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing

Published on: July 6, 2016

Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
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Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants

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The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii
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The Development of Lyophilized Loop-mediated Isothermal Amplification Reagents for the Detection of Coxiella burnetii

Published on: April 18, 2016

  • Diagnosis relies on antibody detection, and treatment involves broad-spectrum antibiotics.

    • Impact:

    • Enhances understanding of Q fever pathogenesis and epidemiology.
    • Informs clinical diagnosis and management of Coxiella burnetii infections.
    • Highlights the importance of livestock health in preventing zoonotic disease transmission.