Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleura of the Lungs01:13

Pleura of the Lungs

10.9K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
10.9K
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

1.1K
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
1.1K
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

6.3K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
6.3K
Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

1.4K
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
1.4K
Pneumothorax-II01:27

Pneumothorax-II

1.7K
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
1.7K
Pneumothorax II: Pathophysiology01:08

Pneumothorax II: Pathophysiology

44
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance...
44

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Developmental genetic determinants of the human cerebrospinal fluid-ventricular system.

Science translational medicine·2026
Same author

Quality of life: a neglected aspect in male infertility studies.

International braz j urol : official journal of the Brazilian Society of Urology·2026
Same author

Advancements in RNA-based therapies from bench to bedside.

npj drug discovery·2026
Same author

Congenital Extraskeletal Ewing's Sarcoma over Forehead.

Journal of Indian Association of Pediatric Surgeons·2026
Same author

Integrating transcriptomics and gene-level interpretable probabilistic Tsetlin Machine reveals elevated pancreatic cancer risk in Type 2 diabetes.

Computational biology and chemistry·2026
Same author

Using Computational Intelligence to Connect Data and Drug Design in Medicinal Chemistry: A Review.

Current drug discovery technologies·2026

Related Experiment Video

Updated: Apr 28, 2026

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
07:40

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis

Published on: March 20, 2021

20.2K

Normoblasts in pleural fluid: are they significant?

Usha Kini1, Amrita Singh

  • 1Department of Pathology, St. John's Medical College and Hospital, Koramangala, Bangalore, India. drushakini@gmail.com

Diagnostic Cytopathology
|August 19, 2007
PubMed
Summary

Isolated normoblasts in body fluids are rarely observed. This study details their first documented appearance in pleural fluid, emphasizing the need for careful differentiation from mesothelial cells.

More Related Videos

The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood
07:17

The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood

Published on: February 7, 2025

1.5K
Rapid Magnetic-microbead Method for Efficient Purification of Low-density Neutrophils
08:14

Rapid Magnetic-microbead Method for Efficient Purification of Low-density Neutrophils

Published on: November 11, 2025

603

Related Experiment Videos

Last Updated: Apr 28, 2026

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis
07:40

Preparation of Peripheral Blood Mononuclear Cell Pellets and Plasma from a Single Blood Draw at Clinical Trial Sites for Biomarker Analysis

Published on: March 20, 2021

20.2K
The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood
07:17

The Isolation and Characterization of Low- and Normal- Density Neutrophils from Whole Blood

Published on: February 7, 2025

1.5K
Rapid Magnetic-microbead Method for Efficient Purification of Low-density Neutrophils
08:14

Rapid Magnetic-microbead Method for Efficient Purification of Low-density Neutrophils

Published on: November 11, 2025

603

Area of Science:

  • Hematology
  • Cytopathology

Background:

  • Hemopoietic cell elements in body fluids are uncommon.
  • Megakaryocytes are occasionally found in pleural and peritoneal fluids due to extramedullary hemopoiesis in myeloproliferative disorders.

Observation:

  • This report describes the novel finding of isolated normoblasts in pleural fluid from two patients.
  • Normoblasts exhibit morphological similarities to mesothelial cells, necessitating careful differentiation.

Findings:

  • The study presents the first documented instance of isolated normoblasts in body fluid cytology.
  • Morphological resemblance to mesothelial cells can lead to diagnostic challenges.

Implications:

  • Accurate differentiation of normoblasts from mesothelial cells is crucial in cytological evaluation.
  • Supravital staining can aid in distinguishing these cell types when uncertain.
  • Further studies with more cases are needed to understand the clinical significance of normoblasts in body fluids.