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The structure-activity relationship of inhibitors of serotonin uptake and receptor binding
1Department of Chemistry, Pomona College, Claremont, CA 91711.
Journal of Computer-Aided Molecular Design
|October 1, 1991
Abstract:
An analysis of five different datasets of inhibitors of serotonin uptake has yielded quantitative structure/activity relationships (QSARs) which delineate the role of steric and hydrophobic properties essential for inhibition by phenylethylamine-type analogues.