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Related Experiment Videos

Pseudocalcification on chest CT scan.

R Tiruvoipati1, S K Balasubramanian, J J Entwisle

  • 1Department of ECMO and Cardiac Surgery, Glenfield Hospital, Groby Road, Leicester LE3 9QP, UK. rtiruvoipati@yahoo.co.uk

The British Journal of Radiology
|August 21, 2007
PubMed
Summary
This summary is machine-generated.

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Liquid ventilation using perfluorocarbons in a pediatric patient with severe respiratory failure led to prolonged lung retention. This retention mimicked pulmonary calcification on CT scans, highlighting the need for cautious interpretation.

Area of Science:

  • Pulmonology
  • Radiology
  • Critical Care Medicine

Background:

  • Liquid ventilation with perfluorocarbons is an advanced therapy for severe respiratory failure.
  • Limited data exists on perfluorocarbon distribution and excretion in pediatric patients undergoing liquid ventilation.

Observation:

  • A 10-year-old girl with miliary tuberculosis received partial liquid ventilation (PLV) with perfluorodecalin via ECMO for severe respiratory failure.
  • Following PLV discontinuation due to pneumothorax, chest CT revealed extensive pulmonary fibrosis and high attenuation lesions resembling calcification.

Findings:

  • Perfluorodecalin samples exhibited Hounsfield unit density similar to the observed high attenuation lesions on CT.
  • This indicates prolonged retention of perfluorocarbons in the lungs, mimicking pulmonary calcification.

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Implications:

  • High-density opacities on chest CT scans in patients who have undergone liquid ventilation require careful interpretation.
  • Radiologists and clinicians should consider perfluorocarbon retention as a potential cause of misleading findings.