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Are aromatic carbon donor hydrogen bonds linear in proteins?

Vikas Nanda1, Ann Schmiedekamp

  • 1Department of Biochemistry, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA. nanda@cabm.rutgers.edu

Proteins
|August 21, 2007
PubMed
Summary

Weak hydrogen bonds involving aromatic carbons are crucial for protein structure. Only charged histidine sidechains strongly favor linear interactions, influencing protein modeling and design.

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