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Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Pilot experience with transhepatic percutaneous renal cryoablation.
John B Malcolm1, Robert Gold, Ithaar H Derweesh
1Department of Urology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Journal of Endourology
|August 21, 2007
Summary
Transhepatic percutaneous cryoablation is a feasible approach for right upper-pole renal tumors. While generally safe, larger tumors may pose increased risks, and local treatment failure can occur.
Area of Science:
- Urology
- Interventional Radiology
- Oncology
Background:
- Percutaneous renal cryoablation is effective for small renal tumors.
- Tumor location can complicate percutaneous access.
- Transhepatic cryoablation offers an alternative approach for specific tumor locations.
Purpose of the Study:
- To evaluate the feasibility of transhepatic percutaneous cryoablation for right upper-pole renal tumors.
- To assess the safety and efficacy of this minimally invasive technique.
Main Methods:
- Three patients (75-87 years old, ASA III-IV) with right upper-pole renal tumors (2-5 cm) underwent transhepatic cryoablation.
- CT-guided cryoprobe placement with two freeze-thaw cycles.
- Transhepatic tract hemostasis achieved with 60-second freeze-thaw cycles.
Main Results:
- Successful percutaneous completion in all cases under conscious sedation.
- Procedure times ranged from 67 to 167 minutes.
- One patient had a perinephric hematoma requiring transfusion; no hepatic complications.
- One case of local treatment failure in a 5-cm mass.
Conclusions:
- Transhepatic access is a feasible method for percutaneous renal cryoablation.
- Tumor size is a limitation, with larger tumors presenting higher risks.
- This technique shows promise for challenging renal tumor locations.
