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Updated: Jul 13, 2026

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Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Surgical vs. percutaneous atrial septal defect closure: Remote effects on left ventricular diastolic function
International Journal of Cardiology
|August 21, 2007
Summary
Surgical closure of atrial septal defects (ASD) may impact left ventricular diastolic function more than device closure. This study compared long-term effects of both ASD treatments on diastolic indices.
Area of Science:
- Cardiology
- Cardiac Surgery
- Echocardiography
Background:
- Atrial septal defects (ASD) were historically treated surgically.
- Device closure is now a preferred method for ASD treatment.
- Understanding long-term cardiac function post-intervention is crucial.
Purpose of the Study:
- To compare the remote effects of surgical versus device closure of ASD.
- To evaluate left ventricular diastolic function indices at least one year post-procedure.
Main Methods:
- Prospective study involving 40 patients (16 device closure, 19 surgical closure).
- Evaluation included mitral inflow and tissue Doppler echocardiography (TDI).
- Comparison with 65 healthy control subjects.
Main Results:
- Significant differences in early mitral inflow velocity E and E/A ratios were observed across all three groups.
- Late diastolic TDI velocities (A') were elevated in both device and surgical closure groups compared to controls.
- Surgical closure showed a more pronounced difference in diastolic indices compared to device closure.
Conclusions:
- Surgical closure of ASD appears to induce more significant alterations in left ventricular diastolic indices than device closure.
- Device closure may offer a potentially less impactful alternative for preserving diastolic function.

