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Updated: Jul 13, 2026

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
Published on: June 10, 2017
Undersized, oversized? It is not one-size-fits-all in lymphoid clonality detection
Abstract:
In clonality assessment in lymphoid malignancies expected size ranges of rearranged Ig/TCR PCR products are relevant and should be taken into account. Yet they should not be employed too strictly, as "undersized" and "oversized" products might still represent true rearrangement products. Now that Ig/TCR clonality testing has technically become relatively easy to perform in routine laboratories, correct interpretation becomes essential and preferably should be organized in close interaction between involved scientists.
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