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Antibacterial prophylaxis in neutropenic patients
1Division of Infectious Disease, University of Genova and San Martino University Hospital, Genova, Italy. viscoli@unige.it
Abstract:
Antibiotic prophylaxis has been used for several decades to prevent infection in chemotherapy-induced neutropenia and its benefits have been debated just as long. Recent analysis suggests that quinolones may actually be life saving in high-risk groups such as acute leukaemia and autologous bone marrow transplant but these benefits are likely to be negated in the long term by the development of quinolone resistance.
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