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Endoscopic treatment of vesicoureteral reflux associated with ureterocele
Boris Chertin1, Nochiparambil Mohanan, Amicur Farkas
1Department of Urology, Shaare Zedek Medical Centre, Jerusalem. bchertin@yahoo.com
Insights
Endoscopic treatment for vesicoureteral reflux (VUR) in children with ureterocele is effective and safe. This minimally invasive approach resolves VUR in most cases, often avoiding open surgery.
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Urologic Oncology
Background:
- Ureteroceles are congenital abnormalities that can lead to complications such as vesicoureteral reflux (VUR).
- VUR, the abnormal backward flow of urine from the bladder to the kidneys, increases the risk of urinary tract infections and renal damage.
- Endoscopic management offers a less invasive alternative to open surgery for VUR associated with ureteroceles.
Purpose of the Study:
- To evaluate the efficacy and safety of endoscopic treatment for VUR in children with ureteroceles.
- To determine the long-term outcomes of this minimally invasive approach.
- To assess the rate of spontaneous resolution and need for further intervention.
Main Methods:
- A retrospective review of 109 children (median age 6 months) who underwent endoscopic ureterocele puncture between 1984 and 2005.
- Ureterocele puncture was performed using a 3Fr Bugbee electrode.
- Indications for surgical correction included high-grade VUR or breakthrough infections; median follow-up was 10 years.
Main Results:
- Spontaneous VUR resolution occurred in 42% of refluxing units after ureterocele puncture.
- Endoscopic correction successfully treated VUR in 70% after one injection and 91% after two injections.
- Overall, 13% of patients experienced VUR to the ureterocele moiety post-puncture, with most managed successfully via endoscopic correction or conservative measures.
Conclusions:
- Endoscopic treatment for VUR associated with ureterocele is a simple, safe, and effective long-term solution.
- This approach successfully avoids open surgery in the majority of pediatric patients.
- Endoscopic ureterocele puncture is a valuable primary treatment option.
Purpose:
We determined the value of endoscopic treatment for vesicoureteral reflux associated with ureterocele.
Materials And Methods:
From 1984 to 2005, 109 children with a median age of 6 months underwent endoscopic ureterocele puncture. Ureterocele presented as a part of a duplex system in 97 of patients (89%) and as part of a single system in 12 (11%). Vesicoureteral reflux was seen to the lower ipsilateral moiety in 53 patients and in 32 contralateral kidneys (85 refluxing renal units). Puncture was performed with a 3Fr Bugbee electrode. High grade vesicoureteral reflux or breakthrough infection while on antibiotic prophylaxis served as the indication for the surgical correction of vesicoureteral reflux. Median followup after endoscopic correction was 10 years (range 1 to 21).
Results:
Spontaneous vesicoureteral reflux resolution following successful ureterocele puncture was seen in 36 of the 85 refluxing renal units (42%) and in 5 (6%) reflux was downgraded. The latter patients were withdrawn from antibiotic prophylaxis and they did well. A total of 33 refluxing renal units with vesicoureteral reflux into the lower moiety of the ureterocele kidney and 11 contralateral refluxing renal units underwent endoscopic correction. Reflux was corrected in 31 of the 44 refluxing renal units (70%) after a single injection and it resolved after a second injection in another 9 (21%). In 4 refluxing renal units (9%) endoscopic correction failed and open reimplantation was done. Of the 109 patients (13%) 14 had vesicoureteral reflux to the ureterocele moiety following endoscopic puncture. Of those patients endoscopic correction resolved reflux in 3, reflux resolved spontaneously in 5 and upper pole partial nephrectomy was performed in 4 due to a nonfunctioning moiety. The remaining 2 patients did well without antibiotic prophylaxis.
Conclusions:
Our data show that endoscopic treatment of vesicoureteral reflux associated with ureterocele is a simple, long-term effective and safe procedure, avoiding the need for open surgery in the majority of patients following endoscopic puncture of ureterocele.
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