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Effects of subchronic exposure to a 1439 MHz electromagnetic field on the microcirculatory parameters in rat brain
Hiroshi Masuda1, Akira Ushiyama, Shogo Hirota
1Department of Environmental Health, National Institute of Public Health, Wako-shi, Saitama, Japan. msd@niph.go.jp
Unlabelled:
THE AIM of this study was to investigate whether repeated exposure to radio frequency electromagnetic field (RF-EMF) of 1439 MHz affects the cerebral microcirculation, including blood-brain barrier function, in a rat brain.
Materials And Methods:
The head of the rat was exposed for four weeks (60 min/day, 5 days/week) to RF-EMF at 2.4 W/kg of brain averaged specific absorption rate (BASAR). Three microcirculatory parameters: blood-brain barrier permeability, leukocyte behavior and plasma velocity were measured before and after RF-EMF exposure using a closed cranial window method.
Results:
No extravasation of intravenously injected dyes from pial venules was found at any BASAR level. No significant changes in the number of endothelial-adhering leukocytes after exposure were found. The plasma velocity remained constant within the physiological range through each exposure.
Conclusion:
These findings suggest that there were no effects on the cerebral microcirculation under the given RF-EMF exposure conditions.
