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Updated: Jul 13, 2026

Large-scale Recording of Neurons by Movable Silicon Probes in Behaving Rodents
Published on: March 4, 2012
Analyzing the activity of large populations of neurons: how tractable is the problem?
Sheila H Nirenberg1, Jonathan D Victor
1Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA. shn201@med.cornell.edu
Abstract:
Understanding how the brain performs computations requires understanding neuronal firing patterns at successive levels of processing-a daunting and seemingly intractable task. Two recent studies have made dramatic progress on this problem by showing how its dimensionality can be reduced. Using the retina as a model system, they demonstrated that multineuronal firing patterns can be predicted by pairwise interactions.
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