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Successful treatment of Ochroconis gallopavum infection in an immunocompetent host

J W Hollingsworth1, S Shofer, A Zaas

  • 1Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University Medical Center, Box 3136, Durham, NC 27710, USA. holli017@mc.duke.edu

Infection
|August 22, 2007
PubMed

Insights

Ochroconis gallopavum, a fungus, rarely causes disease in immunocompromised individuals. This study details the first reported pulmonary infection in an immunocompetent host, successfully treated with oral antifungals.

Area of Science:

  • Medical Mycology
  • Infectious Diseases

Background:

  • Ochroconis gallopavum is a dematiaceous fungus.
  • It is an infrequent cause of disease in immunocompromised patients.
  • The fungus has also been implicated in epidemic encephalitis in poultry.

Observation:

  • This report details the first documented case of active Ochroconis gallopavum pulmonary infection.
  • The patient was an immunocompetent host, challenging the typical understanding of O. gallopavum pathogenicity.
  • The infection presented with pulmonary symptoms.

Findings:

  • The pulmonary infection in the immunocompetent host showed a rapid and complete response to oral antifungal therapy.
  • This suggests a potential treatment avenue for Ochroconis gallopavum infections, even in non-immunocompromised individuals.
  • The specific antifungal agent and dosage led to complete resolution.

Implications:

  • This case expands the known clinical spectrum of Ochroconis gallopavum infections.
  • It highlights the possibility of O. gallopavum causing disease in immunocompetent individuals.
  • Successful treatment with oral antifungals offers a promising therapeutic strategy for similar future cases.

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