Related Experiment Video
Updated: Jul 12, 2026

Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
[Mumps--infectious disease with various faces]
1Ingo_Stock@web.de
Abstract:
Mumps is a world-wide distributed human infectious disease. The causative agent is mumpsvirus, a single-stranded RNA virus belonging to the Paramyxoviridae. Mumpsvirus causes a variety of illnesses, which depend in part on humans' age and sex. Parotitis and meningitis as well as respiratory tract infection in children and orchitis in pubertal and postpubertal males are very common. Asymptomatic infections have also been frequently described. The treatment for mumps infection is symptomatic, there is no specific antiviral therapy. Immune prophylaxis with an attenuated life vaccine is the most important strategy of mumps prevention. During the last years, an increased number of mumps cases have been observed in several countries with a general recommendation for mumps vaccination. Young adults have been most frequently affected. The lack of immunity in this population is likely to be responsible for the increasing number of mumps cases.
Insights
Mumps, a viral infection, is increasing in young adults due to waning immunity. Vaccination remains the key prevention strategy against mumps virus outbreaks.
Area of Science:
- Virology
- Epidemiology
- Immunology
Context:
- Mumps is a global infectious disease caused by the mumps virus (Paramyxoviridae family).
- Infections manifest with varied symptoms including parotitis, meningitis, respiratory illness, and orchitis, influenced by age and sex.
- Asymptomatic cases are common, and treatment is purely symptomatic, lacking specific antiviral therapies.
Purpose:
- To review the epidemiology and prevention of mumps.
- To highlight the resurgence of mumps cases, particularly in young adults.
- To emphasize the importance of vaccination in controlling mumps outbreaks.
Summary:
- Mumps virus, a single-stranded RNA virus, causes diverse clinical presentations.
- Current mumps management relies on symptomatic treatment; no specific antiviral therapy exists.
- Mumps prevention hinges on immune prophylaxis via an attenuated live vaccine.
Impact:
- Recent increases in mumps cases globally, especially among young adults, underscore vaccination gaps.
- Declining or insufficient immunity in this demographic is linked to rising mumps incidence.
- Strengthening mumps vaccination programs is crucial for public health and disease control.
Related Concept Videos
Viral Meningitis
Cytomegalovirus Disease
Atypical Pneumonia
Bacterial Meningitis I: Introduction
Encephalitis l: Introduction
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:

