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Liver candidiasis. The various sonographic patterns in the immunocompromised child
M Grünebaum1, N Ziv, C Kaplinsky
1Department of Pediatric Radiology, Beilinson Medical Center, Petah Tiqva, Israel.
Pediatric Radiology
|January 1, 1991
Summary
This study details liver candidiasis in pediatric oncology patients, highlighting characteristic ultrasound findings like the "wheel in wheel" sign. Early sonographic identification aids in differentiating these fungal infections from other liver pathologies.
Area of Science:
- Medical Imaging
- Hepatology
- Pediatric Oncology
Background:
- Liver candidiasis presents as scattered microabscesses.
- Sonographic identification of these lesions is crucial for diagnosis.
- Distinctive imaging patterns are observed during different disease phases.
Purpose of the Study:
- To describe the sonographic manifestations of liver candidiasis in pediatric oncology patients.
- To discuss the differential diagnosis of these findings.
- To correlate imaging findings with disease progression and healing.
Main Methods:
- Case series involving 4 pediatric oncology patients.
- Detailed sonographic examination of the liver.
- Review of imaging findings and clinical data.
Main Results:
- Observed sonographic patterns included hepatomegaly, "wheel in wheel" phenomenon, "wagon wheel" appearance, and "bull's eye" lesions in the active phase.
- Hypoechoic defects were noted in later stages.
- Echogenic foci indicated the healing phase.
Conclusions:
- Sonography is effective in identifying liver candidiasis in pediatric oncology patients.
- Characteristic imaging findings can aid in diagnosis and monitoring.
- Differentiation from primary liver tumors, metastases, and other abscesses is essential.