Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cyclic adenosine-3',5'-monophosphate level in donor plasma].

N A Fedorov, M A Veske, G V Ermil'chenko

    Biulleten' Eksperimental'Noi Biologii I Meditsiny
    |September 1, 1975
    PubMed
    Summary

    This study on blood donors found cyclic adenosine monophosphate (cAMP) levels vary based on donation history and individual response. Reactive donors showed more significant cAMP level changes after blood donation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Efficiency of a cubic NaI(Tl) detector with rectangular cavity using standard radioactive point sources placed at non-axial position.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2020
    Same author

    New albumin blood substitutes.

    British medical journal·2010
    Same author

    New blood albumin substitute.

    American review of Soviet medicine·2010
    Same author

    [NAT screening of viral infections in donors enhances blood safety].

    Klinicheskaia laboratornaia diagnostika·2007
    Same author

    Frequency of detection of bacterial DNA in whole blood of donors.

    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections·2005
    Same author

    [Application hemostatic drug in capillary-parenchymatous bleeding].

    Khirurgiia·2004

    Area of Science:

    • Biochemistry
    • Endocrinology
    • Hematology

    Context:

    • Investigating the physiological impact of blood donation on key signaling molecules.
    • Utilizing competitive protein binding assays to quantify cyclic adenosine-3',5'-monophosphate (cAMP) levels in plasma.

    Purpose:

    • To analyze changes in plasma cAMP levels in blood donors before and after blood donation.
    • To identify distinct donor subgroups based on their physiological response to blood donation, specifically regarding cAMP levels.

    Summary:

    • The study measured cyclic adenosine-3',5'-monophosphate (cAMP) in donor plasma using Gilman's radiochemical method, one day before and immediately after donating 200 ml of blood.
    • Donors were categorized into 'stable' (no cAMP change) and 'reactive' (cAMP level change) subgroups.

    Related Experiment Videos

  • Repeated donors generally had higher baseline cAMP levels than primary donors. In reactive donors, particularly after blood loss, cAMP levels showed significant fluctuations, often moving towards the mean.

    • Impact:

    • Reveals differential physiological responses to blood donation, highlighting the role of cAMP.
    • Provides insights into donor variability and potential biomarkers for stress response in blood donation.
    • Informs strategies for donor management and understanding the short-term metabolic effects of blood withdrawal.