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Related Concept Videos

Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Conduction System of the Heart01:19

Conduction System of the Heart

Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
Special considerations while measuring pulse01:13

Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
Cardiac Cycle01:29

Cardiac Cycle

The cardiac cycle refers to the sequence of events that occur in the heart from the beginning of one heartbeat to the next. It's characterized by alternating periods of contraction (systole) and relaxation (diastole) of the heart muscles.
During the cardiac cycle, blood flow through the heart is regulated entirely by changing pressure gradients. This sequence of events begins with the heart in a state of total relaxation, known as mid-to-late diastole, during which blood passively flows from...

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Related Experiment Video

Updated: Jul 12, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

[The heartbeat modes in modified Ikeda phase resetting model].

Li Li1, Yang Hong, Li Liu

  • 1Department of Biophysics, China Medical University, Shenyang 110001, China. lilyli@mail.cmu.edu.cn

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi = Journal of Biomedical Engineering = Shengwu Yixue Gongchengxue Zazhi
|August 24, 2007
PubMed
Summary

This study introduces four heartbeat models to simulate cardiac arrhythmias. These models reveal complex dynamics, including bistability and patterns observed in clinical conditions like bigeminy and trigeminy.

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Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
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Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

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Related Experiment Videos

Last Updated: Jul 12, 2026

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

Area of Science:

  • Computational biology
  • Nonlinear dynamics
  • Cardiac electrophysiology

Context:

  • Understanding complex cardiac rhythms is crucial for diagnosing and treating heart conditions.
  • Existing models may not fully capture the intricate interactions between normal and ectopic pacemakers.

Purpose:

  • To develop and analyze novel computational models of heartbeat dynamics.
  • To investigate the influence of ectopic pacemaker location and coupling on heart rhythm.

Summary:

  • Four models based on the modified Ikeda phase resetting model were developed, considering two ectopic pacemaker positions and two coupling styles.
  • Analysis revealed periodic heartbeat modes with "Arnold's tongue" structures and bistable dynamics when the ectopic pacemaker is in the ventricle.
  • Clinical arrhythmias like bigeminy and trigeminy were reproduced under specific conditions of weak coupling or extended refractory periods.

Impact:

  • Provides insights into the mechanisms underlying cardiac arrhythmias.
  • Offers a framework for further research into heart rhythm disorders.
  • Potential applications in developing targeted therapies for arrhythmias.