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Published on: June 29, 2021
[Type IV-allergy due to corticosteroids. Rare and paradoxical]
T Plaza1, G Nist, P von den Driesch
1Klinik für Dermatologie und Allergologie, Zentrum für Hautkrankheiten, Klinikum Stuttgart, Stuttgart, Germany. t.plaza@kbc-intern.de
History And Clinical Findings:
A 48-year-old woman developed a skin rash after taking glucocorticoids.
Investigations:
Positive patch tests revealed type IV allergy (delayed reaction) to several glucocorticoids. In addition an eczema-like rash was produced by an oral provocation test with triamcinolone, although the patch test for this drug had been negative.
Treatment And Course:
We recommended avoidance of the positively-tested corticosteroids and issued a corresponding allergy pass.
Conclusion:
Type IV allergy to glucocorticoids is rare but should be considered whenever patients develop a skin rash after the use of corticosteroids.
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