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Updated: Jul 12, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
Published on: May 1, 2021
miRNomics-The bioinformatics of microRNA genes
Zhumur Ghosh1, Jayprokas Chakrabarti, Bibekanand Mallick
1Computational Biology Group, Indian Association for the Cultivation of Science, 2A & 2B, Raja S.C. Mullick Road, Jadavpur, Calcutta 700032, India.
Abstract:
MicroRNAs (miRNAs) are tiny genetic rheostats in plants, animals, and viruses, regulating the expression of messenger RNAs by targeting transcripts for cleavage or translational repression. Their regulatory impact is even more pervasive as a potential therapeutic tool. Since inception, computational methods have been an invaluable tool complementing experimental approaches. Here, we outline miRNA-bioinformatics highlighting the biological and therapeutic repertoire of miRNAs, in silico prediction of miRNA genes and their targets, along with a glimpse of the bioinformatic challenges that lie ahead.
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