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Assessment of blood pressure in brachial artery(two-step method)

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Related Experiment Video

Updated: Jul 12, 2026

Mechanical Testing of Mouse Carotid Arteries: from Newborn to Adult

Mechanical Testing of Mouse Carotid Arteries: from Newborn to Adult

Published on: February 23, 2012

Carotid artery distensibility: a reliability study.

Elisa Cuadrado Godia¹, Rishi Madhok, John Pittman

¹Department of Neurology, Division of Stroke, Columbia University and Mailman School of Public Health, New York, New York, USA.

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine

|August 24, 2007

Summary

Sonographic measurements of common carotid artery (CCA) diameters show good reproducibility. However, precise boundary identification is crucial for accurate carotid distensibility (CD) metrics in clinical settings.

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Area of Science:

Vascular Ultrasound
Cardiovascular Imaging
Biomedical Engineering

Background:

Carotid distensibility (CD) assesses carotid artery elasticity and is a potential cardiovascular disease risk factor.
Limited information exists on the reproducibility of sonographic CD measurements.
Evaluating inter-reader reliability of common carotid artery (CCA) diameter measurements is essential for clinical application.

Purpose of the Study:

To assess the inter-reader reliability of sonographic measurements of CCA diameters.
To evaluate the reproducibility of derived CD metrics, including strain and elastic modulus.
To determine the clinical utility of sonographic CD measurements.

Main Methods:

Two independent readers measured CCA systolic (SD) and diastolic (DD) diameters from B/M-mode sonography in 118 subjects.
Derived CD metrics (strain, elastic modulus, stiffness, CD) were calculated.
Inter-reader reliability was quantified using type 3 intraclass correlation coefficients (ICC3,1).

Main Results:

High inter-reader reliability was observed for CCA diameters (ICC3,1 = 0.96 for SD, 0.95 for DD).
Mean differences in SD and DD between readers were minimal (0.08 mm and 0.03 mm, respectively).
Demographics correlated with diameters, but not with derived CD metrics or risk factors.

Conclusions:

Sonographic measurement of CCA diameters demonstrates good reproducibility.
Small variations in diameter measurements can significantly impact derived CD metrics like strain and Young's modulus.
Current boundary identification methods may lack the necessary precision for reliable clinical use of CD metrics.