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[Transient hyperglycemia following intra-peritoneal irrigation with 5% glucose in a patient with pseudomyxoma

Rie Mieda1, Chizu Aso, Koichi Nishikawa

  • 1Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi City 371-8511, Japan.

Masui. the Japanese Journal of Anesthesiology
|August 25, 2007
PubMed

Insights

Intra-peritoneal irrigation with glucose for pseudomyxoma peritonei can cause transient hyperglycemia. Monitoring blood glucose levels during and after this procedure is recommended to manage this complication.

Area of Science:

  • Oncology
  • Endocrinology
  • Surgical Complications

Background:

  • Pseudomyxoma peritonei involves neoplastic epithelium producing mucopolysaccharides, leading to mucinous ascites.
  • Complete surgical removal of mucinous ascites is challenging.
  • Intra-peritoneal lavage with glucose or dextrose is used to prevent mucus reaccumulation and complications like bowel obstruction.

Observation:

  • A 72-year-old woman with pseudomyxoma peritonei underwent intra-peritoneal irrigation with 5% glucose solution.
  • The patient developed transient hyperglycemia (serum glucose 266 mg x dl(-1)) shortly after the irrigation procedure.
  • Hemodynamic and oxygenation data remained stable throughout the observation period.

Findings:

  • The patient's hyperglycemia was presumed to be a direct result of the intra-peritoneal glucose instillation.
  • Serum glucose levels returned to 154 mg x dl(-1) one hour post-surgery, indicating a transient effect.
  • No other immediate complications were noted, and the patient recovered uneventfully.

Implications:

  • Awareness of potential acute hyperglycemia is crucial for clinicians performing intra-peritoneal glucose irrigation.
  • Glucose monitoring during and after irrigation is recommended to detect and manage this potentially dangerous complication.
  • This case highlights the importance of vigilant patient monitoring for metabolic disturbances following specific surgical interventions.

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