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Related Experiment Videos

Pediatric bipolar disorder.

Ellen Leibenluft1, Brendan A Rich

  • 1Section on Bipolar Spectrum Disorders, Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda MD, USA. leibs@mail.nih.gov

Annual Review of Clinical Psychology
|August 25, 2007
PubMed
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Research on pediatric bipolar disorder (BD) has surged, with doubled prevalence and publication rates. This review covers diagnostic challenges, pathophysiology, and treatments, focusing on youth with severe irritability.

Area of Science:

  • Child and Adolescent Psychiatry
  • Neuroscience
  • Psychology

Background:

  • Pediatric bipolar disorder (BD) research and interest have significantly increased over the last decade.
  • Prevalence rates in outpatient settings have doubled, and publication output has doubled in the last five years compared to the prior decade.

Purpose of the Study:

  • To review recent developments in the study of pediatric BD.
  • To examine diagnostic boundaries, pathophysiology, and treatment approaches for pediatric BD.
  • To focus on youths with severe chronic irritability, hyperarousal, and hyperreactivity.

Main Methods:

  • Literature review of recent developments in pediatric BD research.
  • Examination of diagnostic criteria, including episodicity and irritability.

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  • Review of pathophysiological data and psychotherapeutic interventions.

    • Main Results:

    • Increased research and prevalence highlight the growing importance of pediatric BD.
    • Diagnostic challenges persist, particularly concerning irritability and differentiating BD from other conditions in youth.
    • Understanding pathophysiology may inform diagnostic accuracy.

    Conclusions:

    • Pediatric BD is a rapidly evolving field requiring careful diagnostic consideration.
    • Psychotherapeutic interventions are a key component of treatment for pediatric BD.
    • Further research is needed, especially for the debated diagnosis in youth with severe irritability and hyperreactivity.