Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Scalable flow synthesis of ultrasmall inorganic nanoparticles for biomedical applications via a confined impinging jet mixer.

Scientific reports·2026
Same author

Open-source robotic chip-to-plate interface for high-throughput microfluidic generation of materials libraries.

bioRxiv : the preprint server for biology·2026
Same author

Conjugate vaccine technology enhances responses to influenza virus.

Vaccine·2026
Same author

Protocol for recombinant expression in E. coli and purification of iBoost vaccine proteins using immobilized metal affinity chromatography.

STAR protocols·2026
Same author

Can nanozymes make the leap to the clinic? Advances, hurdles, and prospects.

Trends in biotechnology·2026
Same author

The vascular contribution to immunotherapy success.

Angiogenesis·2026

Related Experiment Video

Updated: Jul 12, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Magnetic and fluorescent nanoparticles for multimodality imaging.

Willem J M Mulder1, Arjan W Griffioen, Gustav J Strijkers

  • 1Mount Sinai School of Medicine, Imaging Science Laboratories, Department of Radiology, New York, NY 10029, USA. willem.mulder@mountsinai.org

Nanomedicine (London, England)
|August 25, 2007
PubMed
Summary
This summary is machine-generated.

Nanoparticulate contrast agents enhance diagnostic and molecular imaging by offering high contrast payloads and multimodal capabilities. This review surveys fluorescent and magnetic nanoparticles for combined magnetic resonance and optical imaging.

More Related Videos

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
09:43

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Related Experiment Videos

Last Updated: Jul 12, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
09:43

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters

Published on: August 22, 2014

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Medical Imaging

Background:

  • Nanoparticulate contrast agents are increasingly vital in diagnostic and molecular imaging.
  • They offer advantages over traditional agents, including higher contrast material payload and integrated functionalities.
  • Nanoparticle surfaces can be modified for improved pharmacokinetics and targeted delivery.

Purpose of the Study:

  • To review the different types of fluorescent and magnetic nanoparticles.
  • To discuss their application in combined magnetic resonance and optical imaging studies.

Main Methods:

  • Survey of existing literature on nanoparticulate contrast agents.
  • Focus on magnetic resonance imaging (MRI) and optical imaging techniques.
  • Examination of nanoparticle design for multimodal imaging.

Main Results:

  • Nanoparticles can carry high loads of contrast agents for enhanced detectability.
  • Multimodal properties (e.g., magnetic and fluorescent) can be integrated into single nanoparticles.
  • Surface modifications improve nanoparticle circulation and targeting capabilities.

Conclusions:

  • Combining magnetic resonance imaging and optical imaging offers significant advantages.
  • Nanoparticulate contrast agents are a key technology for achieving this multimodal imaging.
  • Fluorescent and magnetic nanoparticles are promising for advanced diagnostic and molecular imaging.