Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

REM Sleep Behavior Disorder01:15

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
Management of Insomnia01:19

Management of Insomnia

The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
Insomnia01:27

Insomnia

Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Sedatives and Hypnotics Drugs: Miscellaneous Agents01:17

Sedatives and Hypnotics Drugs: Miscellaneous Agents

Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physical health and sleep quality as mediators of the stress-cognitive function pathway in community-dwelling older adults.

International psychogeriatrics·2026
Same author

Circadian rhythm sleep disorders and changes in cognitive function and sleepiness among healthcare workers.

Sleep & breathing = Schlaf & Atmung·2026
Same author

A data driven approach to assess relationships between sleep, cognition and dementia: Findings from the Sleep and Dementia Consortium.

medRxiv : the preprint server for health sciences·2025
Same author

Decline in Circadian Robustness in Lung Cancer Patients During Immunotherapy is Associated With Increased Risk of Disease Progression and Death.

Journal of biological rhythms·2025
Same author

Timing of outdoor light exposure is associated with sleep-wake consolidation in community-dwelling older men.

Frontiers in sleep·2025
Same author

The future of sleep apnea management: we can either ride the bus or drive it.

Frontiers in sleep·2025

Related Experiment Video

Updated: Jul 12, 2026

High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster
05:59

High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster

Published on: October 20, 2023

Sleep dysfunction in patients with cancer.

Lavinia Fiorentino1, Sonia Ancoli-Israel

  • 1Sonia Ancoli-Israel, PhD Department of Psychiatry 0603, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. sancoliisrael@ucsd.edu.

Current Treatment Options in Neurology
|August 25, 2007
PubMed
Summary

Cognitive-behavioral therapy (CBT) for insomnia is an effective, non-drug treatment for cancer patients experiencing sleep disturbances. This flexible approach helps improve sleep and reduce anxiety, offering a valuable alternative to medication.

More Related Videos

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Related Experiment Videos

Last Updated: Jul 12, 2026

High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster
05:59

High-Throughput Small Molecule Drug Screening For Age-Related Sleep Disorders Using Drosophila melanogaster

Published on: October 20, 2023

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Oncology
  • Sleep Medicine
  • Behavioral Psychology

Background:

  • Sleep complaints, particularly insomnia, are prevalent among cancer patients.
  • Pharmacotherapy is a common but not always preferred treatment for insomnia in this population.
  • Cancer patients may be hesitant towards additional drug treatments due to existing cancer therapies.

Purpose of the Study:

  • To highlight the efficacy of Cognitive Behavioral Therapy for Insomnia (CBT-I) in cancer patients.
  • To present CBT-I as a viable, non-pharmacological alternative for managing insomnia in oncology.
  • To emphasize the tailored and skills-focused nature of CBT-I for improving sleep and reducing anxiety.

Main Methods:

  • Review of evidence supporting CBT-I for insomnia.
  • Focus on the adaptable and patient-centered approach of CBT-I.
  • Discussion of behavioral and psychological strategies employed in CBT-I.

Main Results:

  • Cognitive-behavioral therapy for insomnia demonstrates effectiveness in cancer patients.
  • CBT-I offers a flexible treatment adaptable to individual patient needs.
  • The therapy focuses on skills to enhance sleep quality and decrease anxiety.

Conclusions:

  • CBT-I is a recommended and effective treatment for insomnia in cancer patients.
  • Its non-pharmacological nature makes it an attractive option for patients managing cancer.
  • CBT-I empowers patients with skills to manage sleep disturbances and associated anxiety.