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Aortic regurgitation: assessment with 64-section CT

Hatem Alkadhi1, Lotus Desbiolles, Lars Husmann

  • 1Institute of Diagnostic Radiology, Clinic for Cardiovascular Surgery, and Cardiovascular Center, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland. hatem.alkadhi@usz.ch

Radiology
|August 25, 2007
PubMed

Insights

64-section computed tomography (CT) accurately assesses aortic regurgitation (AR) by measuring regurgitant orifice area, showing results comparable to transthoracic echocardiography (TTE). This CT method offers reliable diagnostic accuracy for AR severity.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Cardiac Diagnostics

Background:

  • Aortic regurgitation (AR) is a significant valvular heart disease.
  • Accurate assessment of AR severity is crucial for patient management.
  • Transthoracic echocardiography (TTE) is the current standard for AR evaluation.

Purpose of the Study:

  • To prospectively evaluate the diagnostic accuracy of 64-section computed tomography (CT) for assessing aortic regurgitation (AR).
  • To compare CT-derived measurements with transthoracic echocardiography (TTE) as the reference standard.
  • To determine the correlation between CT measurements and AR severity classified by TTE.

Main Methods:

  • Thirty patients with AR underwent both TTE and electrocardiographically gated 64-section CT.
  • CT data were reconstructed to measure the maximum regurgitant orifice area (ROA) in diastole.
  • CT measurements were compared with semiquantitative TTE classification using correlation and ROC analyses.

Main Results:

  • A strong correlation (r=0.84) was found between CT-measured ROA and TTE-based AR severity.
  • CT demonstrated high accuracy in differentiating AR degrees using specific ROA cutoffs (25 mm² and 75 mm²).
  • CT measurements of aortic dimensions and left ventricular parameters correlated well with TTE findings.

Conclusions:

  • 64-section CT provides diagnostic accuracy for assessing aortic regurgitation (AR) that is similar to transthoracic echocardiography (TTE).
  • CT is a valuable tool for evaluating AR severity and associated cardiac dimensions.
  • The findings support the use of 64-section CT in the comprehensive assessment of patients with AR.
Abstract

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