[Functional cardiovascular disorders in patients with neuroses at rest and during physical loading]

The authors examined using selected non-invasive cardiological examination methods 33 patients with neurosis. Four were eliminated on account of organic heart disease. From the group of 29 patients 12 had ECG changes (41%)--of those 5 (17%) had an incomplete right bundle branch block and 1 (3%) had a left anterior fascicular block; 2 (7%) had the syndrome of early repolarization and 4 (14%) had changes of the T wave. The polycardiogram did not reveal a statistically significant difference in the investigated indicators (PEPc, LVETc, WI, PVR) between the group of sick and healthy patients at rest. Ambulatory 24-hour monitoring of the ECG was done in 21 patients--in 2 (10%) it revealed a sinoatrial block, in 10 (50%) episodic sinus tachycardia, in 6 (30%) occasional supraventricular extrasystoles, in 5 (25%) rare ventricular extrasystoles. The echocardiographic examination confirmed the statistically significantly increased systolic function of the left ventricle (P less than 0.05) in all investigated parameters (%D, Vcf, MNSER, EF), as compared with healthy subjects. After a loading ECG test of 28 patients 2 (7%) had ST-T changes. Statistical comparison with the group of healthy subjects revealed in the patients with neurosis a significantly reduced value of systolic (P less than 0.005) and median blood pressure (P less than 0.01), as well as of the inner cardiac work at the peak of the submaximum load (P less than 0.05) and an increase of the diastolic blood pressure (P less than 0.05) during the 10th minute of recovery. The orthostatic test in 20 patients with neurosis revealed a significantly higher heart rate at rest and during the 30th and 60th second after rising (P less than 0.05) and a significantly lower orthostatic index (P less than 0.001) on statistical comparison with healthy subjects.